CBG oil 5%

The isolation of CBG was first announced in 1964, when Y. Gaony and colleagues reported on the structure and partial synthesis of numerous cannabinoids, including CBG.¹ However, since CBG is found in relatively small amounts in most Cannabis varieties, scientists focused on studying the more numerous cannabinoids - THC and CBD.^2-3 In addition to naturally occurring cannabinoids, many synthetic cannabinoid-inspired compounds have been synthesized in recent decades as potential drugs for the pharmaceutical market.^3-4 Some of these chemically modified cannabinoids lack the psychoactive effects attributed to THC, while partially retaining the already known medicinal properties of cannabinoids.^3-4 Unfortunately, synthetic drugs often have drawbacks in the form of residual solvents, and because they are new compounds, they entail serious and sometimes even life-threatening adverse side effects.^5-6 Cannabinoids, on the other hand, have been used for recreational and medicinal purposes for a very long time, and life-threatening side effects from their use have not been reported.⁷ Phytocannabinoids such as CBD, CBN and CBG retain most of the therapeutic effects of THC while having no psychoactive effects. These cannabinoids have shown efficacy in a growing number of diseases and ailments, but the options for their use are still limited for inexplicable reasons and cannabinoids remain inaccessible to the mass public. While there is a wealth of scientific and clinical research on CBD, CBG remains an incompletely understood compound and its therapeutic properties are still under investigation.

1 Gaoni, Y. & Mechoulam, R. Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish. J. Am. Chem. Soc 86, 1646-1647 (1964).

2.Mbvundula, E. C., Rainsford, K. D. & Bunning, R. A. Cannabinoids in pain and inflammation. Inflammopharmacology 12, 99-114 (2004).

3.Wierzbicki, A. S. Rimonabant: endocannabinoid inhibition for the metabolic syndrome. Int. J. Clin. Pract. 60, 1697-1706 (2006).

4 Tai, S. & Fantegrossi, W. E. Synthetic Cannabinoids: Pharmacology, Behavioral Effects, and Abuse Potential. Curr Addict Rep. 1, 129-136 (2014).

5.Gurney, S., Scott, K., Kacinko, S., Presley, B. & Logan, B. Pharmacology, Toxicology, and Adverse Effects of Synthetic Cannabinoid Drugs. Forensic Sci Rev. 26, 53-78 (2014).

6. moreira, F. A. & Crippa, J. A. S. The psychiatric side-effects of rimonabant. Rev. Bras. Psiquiatr. 31, 145-53 (2009).

7.Rosenthal, E. & Kubby, S. Why Marijushould be legal. (Running press, London, 1996).